Article
Retroviral shuttle vectors as a tool for the study of mutational specificity (base substitution/deletion/mutational hotspot).
Mutation research - 1 Jan 2000
Ashman C R
Abstract excerpt
This paper summarizes the use of the retroviral shuttle vector pZipGptNeo for studies of mutational specificity in mammalian cells. This vector was constructed by the introduction of a DNA fragment containing the E. coli gpt gene into the retroviral shuttle vector pZipNeoSV(X)1. The pZipGptNeo vector was then introduced into mouse L cells to construct the A9I2 cell line. Studies utilizing the A9I2 cell line to...
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