Article
Multiple cyclic AMP receptors are linked to adenylyl cyclase in Dictyostelium.
Molecular biology of the cell - 1 Nov 1992
Pupillo M, Insall R, Pitt G S, Devreotes P N
Abstract excerpt
cAMP receptor 1 and G-protein alpha-subunit 2 null cell lines (car1- and g alpha 2-) were examined to assess the roles that these two proteins play in cAMP stimulated adenylyl cyclase activation in Dictyostelium. In intact wild-type cells, cAMP stimulation elicited a rapid activation of adenylyl...
Topics
- Adenylyl Cyclases
- Animals
- Binding Sites
- Blotting, Western
- Cell Division
- Cyclic AMP
- Dictyostelium
- Enzyme Activation
- GTP-Binding Proteins
- Genotype
- Guanosine 5'-O-(3-Thiotriphosphate)
- Guanosine Triphosphate
- Receptors, Cyclic AMP
- Signal Transduction