Article
Multiple cyclic AMP receptors are linked to adenylyl cyclase in Dictyostelium.
Molecular biology of the cell - 1 Nov 1992
Pupillo M, Insall R, Pitt G S, Devreotes P N
Abstract excerpt
cAMP receptor 1 and G-protein alpha-subunit 2 null cell lines (car1- and g alpha 2-) were examined to assess the roles that these two proteins play in cAMP stimulated adenylyl cyclase activation in Dictyostelium. In intact wild-type cells, cAMP stimulation elicited a rapid activation of adenylyl cyclase that peaked in 1-2 min and subsided within 5 min; in g alpha 2- cells, this activation did not occur; in car1-...
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