Article
Protein differences in tau mutant hamsters: candidate clock proteins.
Brain research. Molecular brain research - 1 Sept 1992
Joy J E, Johnson G S, Lazar T, Ralph M R, Hochstrasser A C, Menaker M, Merril C R
Abstract excerpt
In the tau mutant hamster, the period of the circadian rhythm is shortened from about 24 h to about 22 h in heterozygotes and to about 20 h in homozygotes. Understanding the biochemical basis of the period changes in the tau mutant may elucidate the regulation of the vertebrate pacemaker. Using two-dimensional gel electrophoresis, we have found two sets of proteins that differ between the different genotypes....
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