Protein differences in tau mutant hamsters: candidate clock proteins.

doi:10.1016/0169-328x(92)90144-z

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Article

Protein differences in tau mutant hamsters: candidate clock proteins.

Brain research. Molecular brain research - 1 Sept 1992

Joy J E, Johnson G S, Lazar T, Ralph M R, Hochstrasser A C, Menaker M, Merril C R

Abstract excerpt

In the tau mutant hamster, the period of the circadian rhythm is shortened from about 24 h to about 22 h in heterozygotes and to about 20 h in homozygotes. Understanding the biochemical basis of the period changes in the tau mutant may elucidate the regulation of the vertebrate pacemaker. Using t...

Topics

Animals
Biological Clocks
Circadian Rhythm
Cricetinae
Electrophoresis, Polyacrylamide Gel
Genotype
Nerve Tissue Proteins
Photometry
Subcellular Fractions
Suprachiasmatic Nucleus

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