DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.

Article

DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.

The Journal of biological chemistry - 25 Jul 1992

Gunasekera A, Ebright Y W, Ebright R H

Abstract excerpt

The consensus DNA site for binding of the Escherichia coli catabolite gene activator protein (CAP) is 22 base pairs in length and is 2-fold symmetric: 5'-AAATGTGATCTAGATCACATTT-3'. Positions 4 to 8 of each half of the consensus DNA half-site are the most strongly conserved. In this report, we ana...

Topics

5-Methylcytosine
Base Sequence
Cyclic AMP Receptor Protein
Cytosine
DNA, Bacterial
Escherichia coli
Methylation
Molecular Sequence Data
Mutation
Substrate Specificity
Thermodynamics
Thymine
Uracil

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