Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.

The Journal of biological chemistry - 25 Jul 1992

Gunasekera A, Ebright Y W, Ebright R H

Abstract excerpt

The consensus DNA site for binding of the Escherichia coli catabolite gene activator protein (CAP) is 22 base pairs in length and is 2-fold symmetric: 5'-AAATGTGATCTAGATCACATTT-3'. Positions 4 to 8 of each half of the consensus DNA half-site are the most strongly conserved. In this report, we analyze the effects of substitution of DNA base pairs at positions 4 to 8, the effects of substitution of thymine by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Bacterial
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methylation

Share to Molecular Sequence Data

Share to Mutation

Share to Substrate Specificity

Share to Thermodynamics

Source

Identifiers

PMID: 1321815

Genes

GATC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.PMID 1321815Read ↗

Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli.Semantic proximity Read ↗

Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation.Semantic proximity Read ↗

Identification of a contact between arginine-180 of the catabolite gene activator protein (CAP) and base pair 5 of the DNA site in the CAP-DNA complex.Semantic proximity Read ↗

Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site.Semantic proximity Read ↗

Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). I. Saturation and alanine-scanning mutagenesis.Semantic proximity Read ↗

A lethal mutant of the catabolite gene activator protein CAP of Escherichia coli.Semantic proximity Read ↗

Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP). II. Role at Class I and class II CAP-dependent promoters.Semantic proximity Read ↗

A high-throughput percentage-of-binding strategy to measure binding energies in DNA-protein interactions: application to genome-scale site discovery.Semantic proximity Read ↗

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein.Semantic proximity Read ↗

Insights into the quality of DnaA boxes and their cooperativity.Semantic proximity Read ↗

Refining the binding of the Escherichia coli flagellar master regulator, FlhD4C2, on a base-specific level.Semantic proximity Read ↗

CAP interacts with RNA polymerase in solution in the absence of promoter DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.