Article
CAP interacts with RNA polymerase in solution in the absence of promoter DNA.
Nature - 5 Aug 1993
Heyduk T, Lee J C, Ebright Y W, Blatter E E, Zhou Y, Ebright R H
Abstract excerpt
Protein-protein interactions between transcription activator proteins and RNA polymerase or basal transcription factors have been suggested to be important for transcription activation. Interactions between catabolite gene activator protein (CAP) and RNA polymerase have been proposed based on face-of-helix-dependent transcription activation by CAP and based on face-of-helix-dependent cooperative binding of CAP...
Topics
- Base Sequence
- Cyclic AMP Receptor Protein
- DNA
- DNA-Directed RNA Polymerases
- Escherichia coli
- Fluorescence Polarization
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Protein Binding
- Solutions