Article
Disruption of a silencer domain by a retrotransposon.
Genetics - 1 Jul 1992
Mastrangelo M F, Weinstock K G, Shafer B K, Hedge A M, Garfinkel D J, Strathern J N
Abstract excerpt
A galactose-inducible Ty element carrying the HIS3 gene has been used as an insertional mutagen to generate alpha-factor resistant mutants. This collection of Ty-induced mutations includes insertions into the gene for the alpha-factor receptor (STE2), several nonspecific STE genes, and mutations...
Topics
- Blotting, Southern
- DNA Transposable Elements
- Electrophoresis, Gel, Pulsed-Field
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Mating Factor
- Mutagenesis, Insertional
- Peptides
- Phenotype
- Receptors, Cell Surface
- Receptors, Mating Factor
- Receptors, Peptide
- Regulatory Sequences, Nucleic Acid
- Saccharomyces cerevisiae
- Transcription Factors