Substitutions in the hydrophobic core of the alpha-factor receptor of Saccharomyces cerevisiae permit response to Saccharomyces kluyveri alpha-factor and to antagonist.

Abstract excerpt

Mutations in the Saccharomyces cerevisiae alpha-factor receptor that lead to improved response to Saccharomyces kluyveri alpha-factor were identified and sequenced. Mutants were isolated from cells bearing randomly mutagenized receptor gene (STE2) plasmids by an in vivo screen. Five mutations lea...

Topics

• Amino Acid Sequence
• Mating Factor
• Molecular Sequence Data
• Mutation
• Peptides
• Receptors, Cell Surface
• Receptors, Mating Factor
• Receptors, Peptide
• Saccharomyces
• Saccharomyces cerevisiae
• Transcription Factors