Article
Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae.
Genetics - 1 Nov 2004
Aye Michael, Irwin Becky, Beliakova-Bethell Nadejda, Chen Eric, Garrus Jennifer, Sandmeyer Suzanne
Abstract excerpt
The retrovirus-like element Ty3 of Saccharomyces cerevisiae integrates at the transcription initiation region of RNA polymerase III. To identify host genes that affect transposition, a collection of insertion mutants was screened using a genetic assay in which insertion of Ty3 activates expression of a tRNA suppressor. Fifty-three loci were identified in this screen. Corresponding knockout mutants were tested for...
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