Article
Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene.
Blood - 1 Jan 1992
Kennedy M, Beug H, Wagner E F, Keller G
Abstract excerpt
Transplantation of spleen cells from primary reconstituted mice expressing the v-src oncogene to secondary and tertiary irradiated recipients resulted in the emergence of erythroid precursors with a transformed phenotype. When cultured in methyl cellulose, these precursors generated colonies of u...
Topics
- Animals
- Bone Marrow Cells
- Cell Differentiation
- Cell Division
- Cell Line
- Cell Separation
- Cell Transformation, Neoplastic
- Erythroid Precursor Cells
- Erythropoietin
- Gene Expression
- Genes, src
- Growth Substances
- Hematopoietic Cell Growth Factors
- Hematopoietic Stem Cell Transplantation
- Hematopoietic Stem Cells
- Interleukin-3
- Mice
- Phenotype