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Article

Technical approach for the study of the genetic evolution of breast cancer from paraffin-embedded tissue sections.

Breast cancer research and treatment - 1 Jan 1996

Chen T, Dhingra K, Sahin A, Sneige N, Hortobagyi G, Aldaz C M

Abstract excerpt

We have optimized a technique that allows the study of numerous chromosomal loci (n = 20-50) from single paraffin-embedded tissue sections by microsatellite length polymorphism analysis. DNA samples from normal and breast cancerous tissue can be obtained from the same section by means of microdissection. This technique was further improved by subjecting DNA to several cycles of amplification with a degenerate...

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Identifiers

PMID: 8872326
DOI: 10.1007/BF01806184

Genes

ERBB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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