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Article

Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.

Neuroscience letters - 16 Oct 2003

Culpan Doris, MacGowan Sian H, Ford Julia M, Nicoll James A R, Griffin W Sue, Dewar Deborah, Cairns Nigel J, Hughes Anthony, Kehoe Patrick G, Wilcock Gordon K

Abstract excerpt

Recent findings suggest that production of pro-inflammatory cytokines, such as tumour necrosis factor-alpha (TNF-alpha), is increased in the brains of people with Alzheimer's disease (AD). We used direct sequencing methods on a section of the enhancer/promoter region and on a smaller fragment located 10.5 kb upstream of the TNF-alpha gene to respectively examine TNF-alpha polymorphisms and TNF-a and -b...

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Source

Identifiers

PMID: 12962917
DOI: 10.1016/s0304-3940(03)00854-1

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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