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Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's disease.

Brain research reviews - 1 Oct 2009

Di Bona Danilo, Candore Giuseppina, Franceschi Claudio, Licastro Federico, Colonna-Romano Giuseppina, Cammà Calogero, Lio Domenico, Caruso Calogero

Abstract excerpt

It has been hypothesized that polymorphisms of Tumor Necrosis Factor (TNF)-alpha gene affect the risk of developing Alzheimer's disease (AD). However, results of different studies are often inconsistent. Our aim was to investigate by meta-analysis the association of the common polymorphisms comprehensively defining the genetic variability of the TNF-alpha gene with AD risk. Hence, the results being stated are of...

Topics

Alzheimer Disease
Humans
Odds Ratio
Polymorphism, Single Nucleotide
Tumor Necrosis Factor-alpha

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19445962
DOI: 10.1016/j.brainresrev.2009.05.001

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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