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Article

Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease.

Journal of neuroinflammation - 20 Aug 2008

Gnjec Anastazija, D'Costa Katarzyna J, Laws Simon M, Hedley Ross, Balakrishnan Kelvin, Taddei Kevin, Martins Georgia, Paton Athena, Verdile Giuseppe, Gandy Samuel E, Broe G Anthony, Brooks William S, Bennett Hayley, Piguet Olivier, Price Patricia, Miklossy Judith, Hallmayer Joachim, McGeer Patrick L, Martins Ralph N

Abstract excerpt

BACKGROUND: Inflammatory changes are a prominent feature of brains affected by Alzheimer's disease (AD). Activated glial cells release inflammatory cytokines which modulate the neurodegenerative process. These cytokines are encoded by genes representing several interleukins and TNFA, which are associated with AD. The gene coding for HLA-B associated transcript 1 (BAT1) lies adjacent to TNFA in the central major...

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Identifiers

PMID: 18715507
DOI: 10.1186/1742-2094-5-36
PMCID: PMC2538517

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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