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Article

TNFR-associated factor-2 (TRAF-2) in Alzheimer's disease.

Neurobiology of aging - 1 Jul 2009

Culpan Doris, Cram Dougal, Chalmers Kate, Cornish Abigail, Palmer Laura, Palmer Jennifer, Hughes Anthony, Passmore Peter, Craig David, Craigs David, Wilcock Gordon K, Kehoe Patrick G, Love Seth

Abstract excerpt

Levels of tumor necrosis factor-alpha (TNF-alpha) are increased in the brain in Alzheimer's disease (AD). The TNF-alpha/TNF-R signaling pathways involve complex interactions between several proteins, including TNF-receptor-associated factor-2 (TRAF-2). We have examined the distribution and levels of TRAF-2 in AD and control brains and also whether single nucleotide polymorphisms (SNPs) in the TRAF-2 gene are...

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PMID: 18069092
DOI: 10.1016/j.neurobiolaging.2007.10.014

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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