Article
Haplotype structure and evidence for positive selection at the human IL13 locus.
Molecular biology and evolution - 1 Jan 2004
Zhou Gangqiao, Zhai Yun, Dong Xiaojia, Zhang Xiumei, He Fengying, Zhou Kaixin, Zhu Yunping, Wei Handong, Yao Zhijian, Zhong Shaofei, Shen Yan, Qiang Boqing, He Fuchu
Abstract excerpt
Interleukin-13 (IL13) is believed to play an important role in the pathogenesis of atopy and allergic asthma. To better understand genetic variation at the IL13 locus, we resequenced a 5.1-kb genomic region spanning the entire locus and identified 26 single-nucleotide polymorphisms (SNPs) in 74 i...
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