Article
Comprehensive sequence analysis of the human IL23A gene defines new variation content and high rate of evolutionary conservation.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Apr 2010
Tindall Elizabeth A, Hayes Vanessa M
Abstract excerpt
A newly described heterodimeric cytokine, interleukin-23 (IL-23) is emerging as a key player in both the innate and the adaptive T helper (Th)17 driven immune response as well as an initiator of several autoimmune diseases. The rate-limiting element of IL-23 production is believed to be driven by...
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