Article

Positive Selection Affects the Expression of Systemic Lupus Erythematosus Associated Loci in Human Populations

2021-03-01

Abstract excerpt

<h4>Background: </h4> Systemic lupus erythematosus (SLE) shows marked population-specific disparities in disease prevalence, including substantial variation in manifestations and complications according to genetic ancestry. Several recent studies suggest that a substantial proportion of variation of gene expression shows genetic ancestry-associated differences in gene regulation on immune responses. Positive selec...

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Literature Corpus work: 4b187863-9788-5a23-b3d9-17cd1f739649
DOI: 10.21203/rs.3.rs-255082/v1

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