Article
Genetics of IL-13 and functional relevance of IL-13 variants.
Current opinion in allergy and clinical immunology - 1 Oct 2002
Vercelli Donata
Abstract excerpt
Studies in both humans and mice clearly show that interleukin (IL)-13 is a central regulator of allergic inflammation. Numerous single nucleotide polymorphisms have been recently identified in the IL-13 gene and have been found to be associated with allergic and/or asthmatic phenotypes in different populations throughout the world. Furthermore, functional genomics studies are highlighting mechanistic pathways...
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