Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors.

doi:10.1016/0300-483x(95)03112-s

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Article

Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors.

Toxicology - 25 Aug 1995

Maronpot R R, Fox T, Malarkey D E, Goldsworthy T L

Abstract excerpt

The mouse liver is a frequent target organ for chemical carcinogenesis (Huff et al., 1988, 1991; Gold et al., 1989) and tumor development exhibits preferential strain sensitivity (Dragani et al., 1992; Drinkwater and Bennett, 1991). In some reports a positive correlation has been observed between...

Topics

Animals
Carcinogens
Codon
Gene Expression Regulation
Genes, ras
Liver Neoplasms, Experimental
Mice
Mutation
Proto-Oncogene Mas
Species Specificity

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