Article
Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors.
Toxicology - 25 Aug 1995
Maronpot R R, Fox T, Malarkey D E, Goldsworthy T L
Abstract excerpt
The mouse liver is a frequent target organ for chemical carcinogenesis (Huff et al., 1988, 1991; Gold et al., 1989) and tumor development exhibits preferential strain sensitivity (Dragani et al., 1992; Drinkwater and Bennett, 1991). In some reports a positive correlation has been observed between the degree of spontaneous liver tumor incidence and the propensity to develop liver tumors after treatment with...
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