Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of environmental housing conditions on the emotional responses of mice deficient for nociceptin/orphanin FQ peptide precursor gene.

Behavioural brain research - 15 Sept 2003

Ouagazzal A-M, Moreau J-L, Pauly-Evers M, Jenck F

Abstract excerpt

Nociceptin/orphanin FQ (N/OFQ) is a newly discovered neuropeptide that has been implicated in the neurobiological regulation of the behavioral responses to stress and fear. To investigate the role of this peptide in the expression of stress/anxiety-related behaviors in mice, a gene targeting approach to disrupt N/OFQ in the pre-proN/OFQ gene was used. The impact of environmental housing conditions (single and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Emotions
Share to Exploratory Behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurologic Examination

Share to Psychomotor Performance

Share to Reflex, Startle

Share to Restraint, Physical

Share to Swimming

Source

Identifiers

PMID: 12946601
DOI: 10.1016/s0166-4328(03)00066-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of environmental housing conditions on the emotional responses of mice deficient for nociceptin/orphanin FQ peptide precursor gene.PMID 12946601Read ↗

Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice.Semantic proximity Read ↗

Characterization of gene-environment interactions by behavioral profiling of selectively bred rats: the effect of NMDA receptor inhibition and social isolation.Semantic proximity Read ↗

Normal sensitivity to acute pain, but increased inflammatory hyperalgesia in mice lacking the nociceptin precursor polypeptide or the nociceptin receptor.Semantic proximity Read ↗

Nature vs. nurture: can enrichment rescue the behavioural phenotype of BDNF heterozygous mice?Semantic proximity Read ↗

Different housing conditions alter the behavioural phenotype of CCK(2) receptor-deficient mice.Semantic proximity Read ↗

Enriched environment alters the behavioral profile of tenascin-C deficient mice.Semantic proximity Read ↗

Increased fear response to contextual cues in mice lacking the 5-HT1A receptor.Semantic proximity Read ↗

NPY-Y1 coexpressed with NPY-Y5 receptors modulate anxiety but not mild social stress response in mice.Semantic proximity Read ↗

Behavioral phenotype of pre-proenkephalin-deficient mice on diverse congenic backgrounds.Semantic proximity Read ↗

Behavioural profile of a new mouse model for NPY deficiencySemantic proximity Read ↗

Nociceptin Orphanin F/Q Pathways are Dysregulated by Stress and Modulate Reward Learning and Motivation Across SpeciesSemantic proximity Read ↗

Anxiety-like behavior and locomotion in CCK1 knockout rats as a function of strain, sex and early maternal environment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.