Article
Nature vs. nurture: can enrichment rescue the behavioural phenotype of BDNF heterozygous mice?
Behavioural brain research - 10 Oct 2008
Chourbaji Sabine, Brandwein Christiane, Vogt Miriam A, Dormann Christof, Hellweg Rainer, Gass Peter
Abstract excerpt
In earlier experiments we have demonstrated that group-housing in a rather impoverished "standard" environment can be a crucial stress factor in male C57Bl/6 mice. The present study aimed at investigating the effect of combining a probable genetic vulnerability--postulated by the "Neurotrophin Hypothesis of Depression"--with the potentially modulating influence of a stressful environment such as "impoverished"...
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