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Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer.

Cancer research - 15 Aug 2003

Gackowski Daniel, Speina Elzbieta, Zielinska Maja, Kowalewski Janusz, Rozalski Rafal, Siomek Agnieszka, Paciorek Tomasz, Tudek Barbara, Olinski Ryszard

Abstract excerpt

The broad spectrum of oxidative DNA damage biomarkers [urinary excretion of 8-hydroxy-2'-deoxyguanosine (8-OH-dGuo) and 8-hydroxyguanine (8-OH-Gua)] and the level of oxidative DNA damage and repair in leukocytes DNA were analyzed in three groups of subjects: (a) lung cancer patients [all smokers (n = 51)]; (b) healthy smokers with comparable smoking status (n = 26); and (c) healthy nonsmokers (n = 38). The mean...

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PMID: 12941813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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