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Article

[The role of DNA adducts in smoking-related carcinogenesis].

Magyar onkologia - 1 Jan 2004

Schoket Bernadette

Abstract excerpt

Epidemiological studies indicate a close association between smoking and cancer. Biological activity of many chemical carcinogens and of their metabolites is induced by covalent binding of their reactive derivatives to DNA, which consequently causes mutations in critical genes. Carcinogen-DNA adducts formed by exposure to tobacco smoke have a key role in the initiation of various types of cancer including lung...

Topics

DNA Adducts
Humans
Lung Neoplasms
Mutation
Neoplasms
Smoking
Tissue Distribution
Tumor Suppressor Protein p53

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15520869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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