Article
DNA adduct level in lung tissue may act as a risk biomarker of lung cancer.
European journal of cancer (Oxford, England : 1990) - 1 Jul 2000
Cheng Y W, Chen C Y, Lin P, Huang K H, Lin T S, Wu M H, Lee H
Abstract excerpt
Lung cancer is a leading cause of mortality in Taiwan. We hypothesised that high susceptibility to DNA damage in the target organ acts as a risk biomarker for the development of lung cancer. To verify this hypothesis, the aromatic/hydrophobic DNA adduct levels of non-tumorous adjacent lung tissues from 73 primary lung cancer patients and 33 non-cancer controls were evaluated by 32P-postlabelling assay. Wilcoxon...
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