Article
Late onset Alzheimer's disease and apolipoprotein association in the Irish population: relative risk and attributable fraction.
Irish journal of medical science - 1 Jan 2000
Hawi Z, Sheehan K, Lynch A, Evans I, Lowe N, Lawlor B, Gill M
Abstract excerpt
BACKGROUND: Familial and sporadic late onset Alzheimer's disease (LOAD) shows a consistent genetic association with APOE epsilon4. AIMS: To examine the role of APOE in the AD Irish population. METHODS: One hundred and ten Irish LOAD patients and 217 ethnically-matched controls were genotyped for APOE marker as described by Crook et al. Chi square test was used to compare allelic and genotypic frequencies between...
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