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Article

Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: variation by age and sex.

Journal of neurology, neurosurgery, and psychiatry - 1 Jun 2004

Qiu C, Kivipelto M, Agüero-Torres H, Winblad B, Fratiglioni L

Abstract excerpt

BACKGROUND: The risk effect of APOE epsilon 4 allele for Alzheimer's disease is acknowledged, whereas the putative protective effect of epsilon 2 allele remains in debate. OBJECTIVES: To investigate whether those inconsistent findings may be attributable to differences in age and sex composition of the study populations. METHODS: A community dementia free cohort (n = 985) aged > or =75 years was followed up to...

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Identifiers

PMID: 15145993
DOI: 10.1136/jnnp.2003.021493
PMCID: PMC1739059

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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