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Article

The targeted disruption of the CD98 gene results in embryonic lethality.

Biochemical and biophysical research communications - 5 Sept 2003

Tsumura Hideki, Suzuki Noboru, Saito Hiromitsu, Kawano Mitsuo, Otake Seiichi, Kozuka Yuji, Komada Hiroshi, Tsurudome Masato, Ito Yasuhiko

Abstract excerpt

CD98 is one of the important molecules for development, cell differentiation, cell proliferation, and regulation of cellular function. In this study, CD98 heavy chain (HC) knockout mice were produced and analyzed. Five targeted ES clones were obtained and colony frequency was about 2%. One (clone...

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Identifiers

PMID: 12927796
DOI: 10.1016/s0006-291x(03)01473-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12927796-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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