Article
Beta1 integrins show specific association with CD98 protein in low density membranes.
BMC biochemistry - 1 Jan 2001
Kolesnikova T V, Mannion B A, Berditchevski F, Hemler M E
Abstract excerpt
BACKGROUND: The CD98 (4F2, FRP-1) is a widely expressed cell surface protein heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain. Originally described as a T cell activation antigen, it was later shown to function in amino acid transport, cell fusion and homotypic cell aggregation. Several lines of evidence suggest its functional interaction with integrins but the biochemical...
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