Article
Effects of flanking genes on the phenotypes of mice deficient in basigin/CD147.
Biochemical and biophysical research communications - 5 Nov 2004
Chen Sen, Kadomatsu Kenji, Kondo Mineo, Toyama Yoshiro, Toshimori Kiyotaka, Ueno Shinji, Miyake Yozo, Muramatsu Takashi
Abstract excerpt
The induction of null mutations by means of homologous recombination is a powerful technique for clarifying the biological activities of target genes. However, the problems of the genetic background and flanking genes should be borne in mind. Here we employed a breeding strategy to compare three...
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