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Article

A restrictive role for Hedgehog signalling during otic specification in Xenopus.

Developmental biology - 15 Aug 2003

Koebernick Katja, Hollemann Thomas, Pieler Tomas

Abstract excerpt

Vertebrate inner ear development is initiated by the specification of the otic placode, an ectodermal structure induced by signals from neighboring tissue. Although several signaling molecules have been identified as candidate otic inducers, many details of the process of inner ear induction remain elusive. Here, we report that otic induction is responsive to the level of Hedgehog (Hh) signaling activity in...

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Identifiers

PMID: 12921735
DOI: 10.1016/s0012-1606(03)00242-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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