Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock.

Molecular and cellular biology - 1 Sept 2003

Yang Yuhong, Cheng Ping, He Qiyang, Wang Lixin, Liu Yi

Abstract excerpt

FREQUENCY (FRQ), a key component of the Neurospora circadian clock, is progressively phosphorylated after its synthesis. Previously, we identified casein kinase II (CKII) as a kinase that phosphorylates FRQ. Disruption of the catalytic subunit of CKII abolishes the clock function; it also causes severe defects in growth and development. To further establish the role of CKII in clock function, one of the CKII...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to Circadian Rhythm
Share to Cytoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Mutation

Share to Phosphorylation

Share to Protein Kinases

Share to Protein Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 12917343
DOI: 10.1128/MCB.23.17.6221-6228.2003
PMCID: PMC180927

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock.PMID 12917343Read ↗

CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop.Semantic proximity Read ↗

Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock.Semantic proximity Read ↗

FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock.Semantic proximity Read ↗

Transcriptional repression of frequency by the IEC-1-INO80 complex is required for normal Neurospora circadian clock function.Semantic proximity Read ↗

Light-independent phosphorylation of WHITE COLLAR-1 regulates its function in the Neurospora circadian negative feedback loop.Semantic proximity Read ↗

Distinct roles for PP1 and PP2A in the Neurospora circadian clock.Semantic proximity Read ↗

Setting the pace of the Neurospora circadian clock by multiple independent FRQ phosphorylation events.Semantic proximity Read ↗

The genetics of circadian rhythms in Neurospora.Semantic proximity Read ↗

Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination.Semantic proximity Read ↗

Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms.Semantic proximity Read ↗

A role for casein kinase 2 in the mechanism underlying circadian temperature compensation.Semantic proximity Read ↗

Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.