Article
The complex for replication initiation of Escherichia coli.
Chromosoma - 1 Jan 1992
Messer W, Hartmann-Kühlein H, Langer U, Mahlow E, Roth A, Schaper S, Urmoneit B, Woelker B
Abstract excerpt
We probed the complex between oriC and DnaA protein using two types of mutants in oriC. Base changes in the DnaA binding sites, DnaA boxes, had little effect on origin function. Mutations which change the distance between DnaA boxes R3 and R4, on the other hand, inactivated oriC unless the mutation deleted or inserted one complete helical turn. Origins with other 10 base pair insertions in the interval between...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Carrier Proteins
- DNA Replication
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Factor For Inversion Stimulation Protein
- Integration Host Factors