Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The complex of oriC DNA with the DnaA initiator protein.

Research in microbiology - 1 Jan 2000

Messer W, Egan B, Gille H, Holz A, Schaefer C, Woelker B

Abstract excerpt

We describe several experimental approaches relating to the early steps in the initiation of DNA replication at oriC. 1) A matrix is given which enables calculatation of the relative affinity of DnaA boxes for DnaA protein; 2) base changes within single Dna A boxes in oriC have little effect on oriC function; 3) mutations which change the distance between DnaA boxes inactivate oriC, but changes by one helical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Bacterial Proteins
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Binding Sites

Share to DNA-Binding Proteins

Share to Escherichia coli

Share to Genes, Bacterial

Share to Molecular Sequence Data

Source

Identifiers

PMID: 1925008
DOI: 10.1016/0923-2508(91)90018-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The complex of oriC DNA with the DnaA initiator protein.PMID 1925008Read ↗

A comprehensive set of DnaA-box mutations in the replication origin, oriC, of Escherichia coli.Semantic proximity Read ↗

The box VII motif of Escherichia coli DnaA protein is required for DnaA oligomerization at the E. coli replication origin.Semantic proximity Read ↗

The complex for replication initiation of Escherichia coli.Semantic proximity Read ↗

Mutations in the DnaA binding sites of the replication origin of Escherichia coli.Semantic proximity Read ↗

The DnaA box R4 in the minimal oriC is dispensable for initiation of Escherichia coli chromosome replication.Semantic proximity Read ↗

Mutant DnaA proteins defective in duplex opening of oriC, the origin of chromosomal DNA replication in Escherichia coli.Semantic proximity Read ↗

A critical DnaA box directs the cooperative binding of the Escherichia coli DnaA protein to the plasmid RK2 replication origin.Semantic proximity Read ↗

Research on DnaA in the early days.Semantic proximity Read ↗

A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin.Semantic proximity Read ↗

Origin recognition is the predominant role for DnaA-ATP in initiation of chromosome replication.Semantic proximity Read ↗

The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome.Semantic proximity Read ↗

DnaA Protein of Escherichia coli: oligomerization at the E. coli chromosomal origin is required for initiation and involves specific N-terminal amino acids.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.