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Article

Diverse dealings of the Werner helicase/nuclease.

Science of aging knowledge environment : SAGE KE - 6 Aug 2003

Cheng Wen-Hsing, Bohr Vilhelm A

Abstract excerpt

The human Werner syndrome is a model for the process of aging. The protein that is mutated in Werner syndrome, WRN, exhibits three catalytic activities: a 3'-to-5' helicase, a 3'-to-5' exonuclease, and an adenosine triphosphatase activity. WRN interacts with a variety of proteins and has been implicated in many aspects of DNA metabolism. A recent paper by Chen et al. published in the August 2003 issue of Aging...

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Source

Identifiers

PMID: 12904570
DOI: 10.1126/sageke.2003.31.pe22

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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