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Recent Advances in Understanding Werner Syndrome

28 Sept 2017

Abstract excerpt

Aging, the universal phenomenon, affects human health and is the primary risk factor for major disease pathologies. Progeroid diseases, which mimic aging at an accelerated rate, have provided cues in understanding the hallmarks of aging. Mutations in DNA repair genes as well as in telomerase subunits are known to cause progeroid syndromes. Werner syndrome (WS), which is characterized by accelerated aging, is an...

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PMID: 29043077
DOI: 10.12688/f1000research.12110.1

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