Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association between an exon 1 CTLA-4 gene polymorphism A(49)G and multiple sclerosis in a Polish population of the Lower Silesia region.

Archivum immunologiae et therapiae experimentalis - 1 Jan 2003

Boćko Dorota, Bilińska Małgorzata, Dobosz Tadeusz, Zołedziewska Magdalena, Suwalska Katarzyna, Tutak Anna, Gruszka Ewa, Frydecka Irena

Abstract excerpt

Multiple sclerosis (MS) a chronic inflammatory demyelinating disease of the central nervous system is believed to have a T cell-mediated autoimmune etiology. The cytotoxic T lymphocyte antigen 4 (CTLA-4) gene is a strong candidate for the involvement in autoimmune diseases because CTLA-4 plays an important role in the downregulation of the early and late stages of T cell activation and the maintenance of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Antigens, Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Heterozygote

Share to Multiple Sclerosis

Share to Poland

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 12894875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between an exon 1 CTLA-4 gene polymorphism A(49)G and multiple sclerosis in a Polish population of the Lower Silesia region.PMID 12894875Read ↗

CTLA-4 +49 A/G gene polymorphism in Croatian and Slovenian multiple sclerosis patients.Semantic proximity Read ↗

Cytotoxic T lymphocyte associated antigen-4 exon 1 A/G polymorphism in Iranian patients with multiple sclerosis.Semantic proximity Read ↗

No evidence for association of CTLA-4 gene polymorphisms with the risk of developing multiple sclerosis: a meta-analysis.Semantic proximity Read ↗

The CTLA-4 gene is associated with multiple sclerosis.Semantic proximity Read ↗

CTLA4 exon 1 dimorphism is associated with primary progressive multiple sclerosis.Semantic proximity Read ↗

Progression of multiple sclerosis is associated with exon 1 CTLA-4 gene polymorphism.Semantic proximity Read ↗

Ctla4 and multiple sclerosis in the Italian population.Semantic proximity Read ↗

[Polymorphism A/G in position +49 of CTLA4 exon 1 in multiple sclerosis in Russians].Semantic proximity Read ↗

CTLA-4 gene polymorphisms (-318C/T, +49A/G, +6230A/G) in Iranian patients with multiple sclerosis.Semantic proximity Read ↗

The CTLA4 +49 A/G*G-CT60*G haplotype is associated with susceptibility to multiple sclerosis in Flanders.Semantic proximity Read ↗

Cytotoxic T lymphocyte antigen-4 +49A/G polymorphism does not affect susceptibility to autoimmune hepatitis.Semantic proximity Read ↗

CTLA4 gene polymorphisms and multiple sclerosis in Northern Ireland.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.