Article
Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected].
The Journal of biological chemistry - 3 Oct 2003
Tang Eric D, Inohara Naohiro, Wang Cun-Yu, Nuñez Gabriel, Guan Kun-Liang
Abstract excerpt
The nuclear factor kappaB (NF-kappaB)/Rel family of transcription factors participates in a wide range of biological activities including inflammation, immunity, and apoptosis. NF-kappaB is kept inactive in the cytoplasm in unstimulated cells by virtue of the masking of its nuclear localization s...
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