Article
MEI-1/katanin is required for translocation of the meiosis I spindle to the oocyte cortex in C elegans.
Developmental biology - 1 Aug 2003
Yang Hsin-ya, McNally Karen, McNally Francis J
Abstract excerpt
In most animals, successful segregation of female meiotic chromosomes involves sequential associations of the meiosis I and meiosis II spindles with the cell cortex so that extra chromosomes can be deposited in polar bodies. The resulting reduction in chromosome number is essential to prevent the generation of polyploid embryos after fertilization. Using time-lapse imaging of living Caenorhabditis elegans oocytes...
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