Article
Premature microtubule-dependent cytoplasmic streaming in cappuccino and spire mutant oocytes.
Science (New York, N.Y.) - 30 Sept 1994
Theurkauf W E
Abstract excerpt
Embryonic axis specification in Drosophila melanogaster is achieved through the asymmetric subcellular localization of morphogenetic molecules within the oocyte. The cappuccino and spire loci are required for both posterior and dorsoventral patterning. Time-lapse confocal microscopic analyses of living egg chambers demonstrated that these mutations induce microtubule reorganization and the premature initiation of...
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