Article
Caenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1.
Molecular biology of the cell - 1 Apr 2014
Connolly Amy A, Osterberg Valerie, Christensen Sara, Price Meredith, Lu Chenggang, Chicas-Cruz Kathy, Lockery Shawn, Mains Paul E, Bowerman Bruce
Abstract excerpt
In many animals, including vertebrates, oocyte meiotic spindles are bipolar but assemble in the absence of centrosomes. Although meiotic spindle positioning in oocytes has been investigated extensively, much less is known about their assembly. In Caenorhabditis elegans, three genes previously shown to contribute to oocyte meiotic spindle assembly are the calponin homology domain protein encoded by aspm-1, the...
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