Article
Localization of the mei-1 gene product of Caenorhaditis elegans, a meiotic-specific spindle component.
The Journal of cell biology - 1 Jul 1994
Clark-Maguire S, Mains P E
Abstract excerpt
Genetic evidence suggests that the product of the mei-1 gene of Caenorhabditis elegans is specifically required for meiosis in the female germline. Loss-of-function mei-1 mutations block meiotic spindle formation while a gain-of-function allele instead results in spindle defects during the early...
Topics
- Adenosine Triphosphatases
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Epistasis, Genetic
- Female
- Gene Expression Regulation
- Genes, Helminth
- Germ Cells
- Helminth Proteins
- Immunohistochemistry
- Male
- Meiosis
- Models, Genetic
- Mutation
- Spindle Apparatus