Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional evaluation of novel single nucleotide polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes.

Molecular carcinogenesis - 1 Jul 2003

Han Weiguo, Pentecost Brian T, Spivack Simon D

Abstract excerpt

Interindividual variation in the expression of the carcinogen- and estrogen-metabolizing enzymes cytochrome P4501B1 and 1A1 (CYP1B1 and CYP1A1) has been detected in human lung. To search for polymorphisms with functional consequences for CYP1B1 and CYP1A1 gene expression, we examined 1.5 kb of th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Phytogenic
Share to Cytochrome P-450 CYP1A1
Share to Cytochrome P-450 CYP1B1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Luciferases

Share to Polycyclic Aromatic Hydrocarbons

Share to Resveratrol

Share to Ribonucleotide Reductases

Share to Stilbenes

Source

Identifiers

PMID: 12884367
DOI: 10.1002/mc.10132

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12884367-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional evaluation of novel single nucleotide polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes.PMID 12884367Read ↗

Allele-specific induction of IL1B -31T/C promoter polymorphism by lung carcinogens.Semantic proximity Read ↗

Single nucleotide polymorphism analysis and functional characterization of the human Ah receptor (AhR) gene promoter.Semantic proximity Read ↗

Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study.Semantic proximity Read ↗

Increased transcriptional activity of the CYP3A4*1B promoter variant.Semantic proximity Read ↗

Characterization of common CYP1B1 variants with different capacity for benzo[a]pyrene-7,8-dihydrodiol epoxide formation from benzo[a]pyrene.Semantic proximity Read ↗

Polymorphisms in the human paraoxonase (PON1) promoterSemantic proximity Read ↗

Differential promoter activities of functional haplotypes in the 5'-flanking region of human sulfotransferase 1A1.Semantic proximity Read ↗

Regulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B of the human APC gene.Semantic proximity Read ↗

Novel CYP2C9 promoter variants and assessment of their impact on gene expression.Semantic proximity Read ↗

Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and AHR, CYP1A1, CYP1A2, or CYP1B1 genotype.Semantic proximity Read ↗

Characterization of new mutations in the coding sequence and 5'-untranslated region of the human prostacylcin synthase gene (CYP8A1).Semantic proximity Read ↗

Identification and functional analyses of polymorphism haplotypes of protein phosphatase 2A-Aα gene promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.