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Article

Novel CYP2C9 promoter variants and assessment of their impact on gene expression.

Molecular pharmacology - 1 Jun 2008

Kramer Melissa A, Rettie Allan E, Rieder Mark J, Cabacungan Erwin T, Hines Ronald N

Abstract excerpt

There are a considerable number of reports identifying and characterizing genetic variants within the CYP2C9 coding region. Much less is known about polymorphic promoter sequences that also might contribute to interindividual differences in CYP2C9 expression. To address this problem, approximately 10,000 base pairs of CYP2C9 upstream information were resequenced using 24 DNA samples from the Coriell Polymorphism...

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Share to Aryl Hydrocarbon Hydroxylases
Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Genetic Variation

Share to Mexican Americans

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Tumor Cells, Cultured

Source

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Identifiers

PMID: 18310303
DOI: 10.1124/mol.107.044149
PMCID: PMC2413059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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