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Article

Allele-specific induction of IL1B -31T/C promoter polymorphism by lung carcinogens.

Mutation research - 30 Oct 2008

Hart Kent, Haugen Aage, Zienolddiny Shanbeh

Abstract excerpt

Environmental and occupational toxicants may induce pulmonary inflammation. Chronic inflammation has been linked to several human diseases and also to initiation and promotion of cancer. Generation of reactive oxygen/nitrogen species (ROS/RNS), secretion of cytokines, chemokines and pro-angiogenic factors are believed to play a role. Interleukin IL-1beta, encoded by the IL1B gene, is a key cytokine produced and...

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Source

Identifiers

PMID: 18656550
DOI: 10.1016/j.mrgentox.2008.06.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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