Article
Single nucleotide polymorphism analysis and functional characterization of the human Ah receptor (AhR) gene promoter.
Archives of biochemistry and biophysics - 1 Jan 2004
Racky Judith, Schmitz Hans-Joachim, Kauffmann Hans-Martin, Schrenk Dieter
Abstract excerpt
The aryl hydrocarbon receptor (AhR) mediates biological and toxicological actions of e.g., halogenated aromatic hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. Although much is known about the biochemical and molecular mechanisms of AhR action, little is known about the control of the expression of the AhR gene itself. Therefore, we aimed at the identification and characterization of regions important...
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