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Article

VHL tumor suppressor gene: its mutation and protein level in renal cell carcinoma.

Oncology reports - 1 Jan 2000

Tsutsumi Hisashi, Miyamoto Chikara, Furuichi Yasuhiro, Yoshiike Miki, Nozawa Shiari, Iwamoto Teruaki

Abstract excerpt

In this study, we identified mutations in the von Hippel-Lindau gene (VHL) in patients with sporadic clear cell renal carcinoma and analyzed the relationship between these VHL mutations and VHL protein (pVHL) expression levels. Analysis of VHL coding region mutations by direct polymerase chain reaction in 39 patients with clear cell renal carcinoma, who had all undergone radical nephrectomy, revealed heterozygous...

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Source

Identifiers

PMID: 12883707

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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