Article
Von Hippel-Lindau disease and sporadic renal cell carcinoma.
Cancer surveys - 1 Jan 1995
Zbar B
Abstract excerpt
The VHL gene, isolated by positional cloning, encodes a protein of 284 aminoacids that has no homology with other proteins in the databases. The nucleotide sequence lacks domains that would suggest (a) a DNA binding protein, (b) nuclear localization, (c) enzymatic activity or (d) membrane localization. Studies are in progress on the size and cellular localization of the VHL protein and how it may function in...
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