Article
Determination of vhl gene mutations in sporadic renal cell carcinoma.
European urology - 1 Jun 2006
Giménez-Bachs José Miguel, Salinas-Sánchez Antonio S, Sánchez-Sánchez Francisco, Lorenzo-Romero Juan G, Donate-Moreno María José, Pastor-Navarro Héctor, García-Olmo Dolores C, Escribano-Martínez Julio, Virseda-Rodríguez Julio A
Abstract excerpt
OBJECTIVE: Characterization of the molecular status of the vhl gene and its relationship to the usual prognostic factors could help establish new diagnostic and therapeutic strategies. This study determines the presence of vhl gene mutations in tumor tissue from patients with sporadic renal cell carcinoma, the relationship between the mutations and classic prognostic factors, and the possible impact on protein...
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