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Article

The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2007

Kaelin William G

Abstract excerpt

Germ line VHL tumor suppressor gene loss-of-function mutations cause von Hippel-Lindau disease, which is associated with an increased risk of central nervous system hemangioblastomas, clear cell renal carcinomas, and pheochromocytomas. Somatic VHL mutations are also common in sporadic clear cell...

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Source

Identifiers

PMID: 17255293
DOI: 10.1158/1078-0432.CCR-06-1865

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17255293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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