Article
Contribution of genetic factors to renal lesions in the stroke-prone spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 2003
Gigante Bruna, Rubattu Speranza, Stanzione Rosita, Lombardi Alessia, Baldi Alfonso, Baldi Feliciano, Volpe Massimo
Abstract excerpt
Stroke-prone spontaneously hypertensive rats (SHRSP) develop renal lesions more frequently than the closely related control strain, the stroke-resistant SHR. The aim of this study was to investigate the contribution of genetic factors to the enhanced susceptibility to renal damage of SHRSP in an SHRSP/SHR F2 intercross by means of a genotype/phenotype cosegregation analysis. For this purpose, 154 6-week-old...
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